Author

H. Hase

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Open access Sep 2026

An ALKBH3 Inhibitor HUHS199 Suppresses Proliferation of Glioblastoma Cells by Targeting 1‐Methyladenosine on GADD45A mRNA

Findings suggest that ALKBH3 promotes GBM cell proliferation via m1A demethylation of GADD45A mRNA, and presents HUHS199 as a first‐in‐class candidate for GBM treatment.

Manami Yamada, H. Hase, Honoka Kitamura et al. · Chemical Biology and Drug De... · 0 citations

Open access Jul 2026

Integrated multi-omics analysis reveals a pH-driven metabolic and translational switch in Ureaplasma parvum

ABSTRACT Human ureaplasmas are minimal-genome bacteria and pathobionts of the urogenital tract. They must adapt to fluctuating pH conditions despite the absence of canonical transcriptional regulatory systems. However, the mechanisms underlying these responses remain unclear. This study aimed to construct a system-leve...

H. Hase, Y. Nakura, Yuki Shimada et al. · Microbiology spectrum · 0 citations