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Review Open access Jul 2026

Targeting Classical EGFR Mutations in Lung Cancer: Twenty Years of Progress and Beyond

Simple Summary Classical EGFR mutations have transformed the management of non-small cell lung cancer across metastatic, resectable, and unresectable locally advanced settings. This review traces the evolution from early-generation EGFR tyrosine kinase inhibitors to osimertinib and contemporary combination regimens, an...

Y. Uehara, H. Hatano, Jia-Tao Zhang et al. · 0 citations

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