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Author

H. Heerspink

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Open access Aug 2026

Finerenone in hypertensive non-diabetic chronic kidney disease: a FIND-CKD subgroup analysis.

BACKGROUND AND AIMS Hypertension is a common attributable cause of chronic kidney disease (CKD). Mineralocorticoid receptor overactivation can lead to hypertension and contributes to CKD progression. In FIND-CKD, finerenone reduced kidney function decline in participants with CKD without diabetes. This prespecified FIN...

H. Heerspink, Jelle M. Beernink, R. Agarwal et al. · 0 citations
Open access Sep 2026

Initial Changes in eGFR during Treatment with Balcinrenone and Dapagliflozin: An Exploratory Analysis of the MIRO-CKD Trial.

INTRODUCTION The novel non-steroidal mineralocorticoid receptor antagonist balcinrenone in combination with dapagliflozin reduced urinary albumin-to-creatinine ratio (UACR) over 12 weeks in the MIRO-CKD phase 2 trial in chronic kidney disease (CKD) and induced a modest acute eGFR reduction upon treatment initiation. Th...

H. Heerspink, Erika de Sousa Amorim, Jelle M. Beernink et al. · 0 citations

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