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Open access Aug 2026

JI-CS004, a chloroform fraction of SH003, induces reactive oxygen species-dependent intrinsic apoptosis via endoplasmic reticulum stress-associated mitochondrial dysfunction in human colorectal cancer cells

Conventional therapies for colorectal cancer (CRC) are often limited by toxicity and therapeutic resistance. Alternative therapeutic strategies are therefore needed. Natural product-derived compounds have been explored as potential anticancer agents. The molecular mechanisms underlying the anticancer effects of JI-CS00...

Taehyoun Kim, Kwang-Jin Cho, H. Hwang et al. · 0 citations

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