Review
Open access
Sep 2026
Dopamine-replacing gene therapy for Parkinson's disease: biochemical background and current clinical experience.
This review summarizes the metabolism, physiological functions, and pathophysiology of dopamine in the striatum and discusses clinical studies investigating gene transfer of dopamine-synthesizing enzymes into the striatum.
H. Ichinose, Yo Sato, Shin-ichi Muramatsu
· Expert Opinion on Biological... · 0 citations