Exercise and Phytochemicals as Modulators of Redox Homeostasis in Aging.
Reduced resilience to physiological stress, including impaired redox signaling, is a hallmark of aging that contributes to chronic disease risk. The transcription factor Nrf2 is widely considered a master regulator of redox homeostasis. Although exercise is a potent activator of Nrf2 signaling, exercise-induced Nrf2 ac...