Author

H. Joe

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Open access Sep 2026

Discovery of ERα‐Targeting Phytochemicals With In Vitro Cytotoxicity and Computational Prediction of Y537S Mutant Inhibition

The result shows that mutated ERα can be potentially targeted by bioactive phytochemical scaffolds found through molecular modeling, presenting a potential therapeutic strategy for metastatic breast cancer resistant to therapies such as tamoxifen.

De-Jun Jiang, O. Kwon, H. Joe et al. · Chemical Biology and Drug De... · 0 citations

Open access Jul 2026

Gooseberry, citrus peel, and licorice extracts as multi-target modulators of inflammatory and metabolic pathways in LPS-induced muscle wasting: integrative network pharmacology and computational docking analysis

Gooseberry, licorice, and citrus peel extracts exhibit multi-pathway muscle-protective effects through coordinated modulation of oxidative stress, inflammation, and TGF-β signaling, suggesting that the ADAMTSL3 rs4842838 variant disrupted TGF-β signaling and contributed to muscle wasting through dysregulated inflammato...

Sunmi Park, Chen Li, H. Joe et al. · Applied Biological Chemistry · 0 citations