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H. Kim

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Open access Jul 2026

Zinc-mediated lysosomal activation by 1H10 enhances autophagy and attenuates tau pathology in Alzheimer's disease models.

Findings indicate that zinc-mediated lysosomal activation by 1H10 enhances the autophagy-lysosomal pathway and attenuates tau pathology in AD models, suggesting that targeting lysosomal function may represent a potential therapeutic strategy for neurodegenerative disorders characterized by impaired proteostasis.

Jae-Won Eom, Ki-Ryeong Kim, Dong-Hyuk Kim et al. · 0 citations
Aug 2026

Anoctamin 2 deletion alters dopamine-related signaling and impairs inhibitory behavioral control in mice.

These findings identify ANO2 as a potential modulator of dopamine-related signaling and inhibitory behavioral control, expanding current understanding of calcium-activated chloride channel function in neural circuits relevant to behavioral domains implicated in neuropsychiatric disorders.

E. Cho, Jooeun Bae, J. Song et al. · 0 citations