Review
Open access
Aug 2026
Targeting splicing-derived neoantigens for precision cancer immunotherapy
This review integrates current understanding of the biological origins, immunological barriers, target classes of splicing neoantigens, and the technologies that enable their advancement in cancer immunotherapy to produce two major classes of immunotherapeutic targets.
Mu-Tian Tang, H. L. Grimes, Nathan Salomonis
· Frontiers in Immunology · 0 citations