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Open access Aug 2026

ExpoLib: a framework for an MS/MS exposome library of anthropogenic and natural toxicants and their biotransformation products

Despite technological advancements over the last three decades in small-molecule omics, compound annotation remains a major bottleneck in untargeted metabolomics and non-targeted environmental analysis. This is especially true for exposomics applications, which remain significantly affected by the limited chemical spac...

V. V. Hernandes, Miguel A. Aguilar Ramos, R. Breinbauer et al. · 0 citations
Open access Oct 2026

Click-to-Release Reactivity of Quaternary Anilinium Tetrazines Enables Cascade Assembly of Multifunctional Biomolecular Scaffolds.

Click chemistry has evolved from its origins in forming covalent connections to also include breaking bonds, cleaving linkers, and liberating cargo, creating broad applications in chemical biology and biomedicine. The reaction sequences that drive these tools are complex, and thus prone to an array of dead-end intermed...

Markus Staudt, C. Poulie, A. Löffler et al. · 0 citations

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