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Author

H. Moutsopoulos

2 papers indexed here

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Review Open access Sep 2026

Autoimmune diseases: distinct disorders or diverse manifestations of a common pathogenic process?

Autoimmune diseases arise from the amplification of natural autoreactive immune clones in genetically susceptible individuals under the influence of environmental triggers, epigenetic modifications, and hormonal factors. They comprise a broad and heterogeneous group of disorders characterized by immune-mediated tissue...

H. Moutsopoulos · 0 citations
Review Open access Sep 2026

FcRn Inhibition in Autoantibody-Mediated Autoimmune Diseases: From Broad Immunosuppression to Precision IgG Modulation

The therapeutic landscape of autoimmune disease is undergoing a conceptual transition. For decades, treatment has relied predominantly on broad immunosuppression, which has substantially reduced morbidity and mortality but remains limited by systemic toxicity and impaired host defence. Advances in molecular immunology...

G. Chrousos, F. Skopouli, H. Moutsopoulos · 0 citations

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