Author

H. Onizuka

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Open access Oct 2026

Inflammatory protein profiling shows limited ability to distinguish sepsis from sepsis mimics

Sepsis mimics resemble sepsis clinically but may require different treatments. We evaluated whether inflammatory protein profiles could distinguish these conditions in a retrospective case-control study using 4 prospective Japanese cohorts. The study included 34 adults with sepsis and 46 with sepsis mimics. We measured...

D. Kasugai, H. Onizuka, A. Numaguchi et al. · medRxiv · 0 citations

Open access Aug 2026

ST6GAL1-mediated sialyl linkage switching drives cancer-promoting α2,6-sialo-protrusions radiating from anti-inflammatory TAMs.

Tumor-associated macrophages (TAMs) are functionally diverse effector cells in the tumor microenvironment (TME). Pro- and anti-inflammatory TAMs are central to cancer progression by shaping inflammation and immune homeostasis, but it remains unknown if polarization-induced remodeling of the TAM glycocalyx critical for...

Priya Dipta, Naaz Bansal, A. Chien et al. · Proceedings of the National... · 0 citations