Psychiatric syndromes can be caused by underlying autoimmune encephalitis (AE). This represents a diagnostic challenge at the interface of psychiatry and neurology. While AE mostly manifests with a combined, complex neuropsychiatric syndrome, some patients with AE may (initially) present with predominant or isolated ps...
D. Endres, K. von Zedtwitz, Ludger Tebartz van Elst et al.· Molecular Psychiatry· 0 citations
Myasthenia gravis (MG) is an autoimmune neuromuscular disorder mediated by autoantibodies targeting the nicotinic acetylcholine receptor (nAChR), which can lead to severe disability and life-threatening crises. Current therapies rely on broad immunosuppression and fail to achieve sustained remission in the majority of...
Niels von Wardenburg, G. Spagni, S. Reincke et al.· Nature Communications· 0 citations
BACKGROUND
Many patients with N-methyl-D-aspartate receptor (NMDAR) encephalitis show persistent neurological or psychiatric symptoms, despite immunotherapy. The neuroanatomical basis of these symptoms remains uncertain. Morphological complexity analysis with fractal dimensionality has emerged as a sensitive neuroimagi...
S. Krohn, G. Cammá, Wei Zhao et al.· Lancet psychiatry· 3 citations
Spatial navigation is identified as a frequently affected but under-assessed cognitive domain in post-acute NMDAR and LGI1 encephalitis, providing clinical evidence that navigation and episodic memory are partially dissociable yet overlapping functions whose degree of separability varies with the extent and distributio...
Sophia Rekers, K. Wurdack, M. Mantwill et al.· bioRxiv· 0 citations
Reductions in both FD and volume in frontotemporal cortices and subcortical areas were associated with impaired overall cognition, with FD more frequently emerging as the dominant measure in brain-cognition associations.
Wei Zhao, K. Wurdack, F. Bartels et al.· Neurology(R) neuroimmunology...· 0 citations
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