Open access
Aug 2026
A targetable dependency on nonsense-mediated decay for cellular homeostasis and immune control in small cell lung cancer
Small cell lung cancer (SCLC) is one of the most aggressive malignancies, characterized by rapid metastatic dissemination and poor overall survival. Despite harboring excessive alterations, expectedly resulting in immunogenic neoantigens, patients with SCLC remain largely refractory to immunotherapy. We found abundant...
Lucia A. Torres-Fernández, V. Boehm, Joel Kaufmann et al.
· Molecular Cancer · 0 citations