Arginase-1 as a biomarker of hemolytic burden in sickle cell anemia and β-thalassemia: A comparative study with healthy controls
Chronic hemolysis is a central feature of sickle cell anemia (SCA) and β-thalassemia and contributes to vascular dysfunction through disruption of arginine metabolism and nitric oxide homeostasis. Arginase-1 has emerged as a potential mediator of these processes; however, comparative evidence across major hemoglobi...