The therapeutic efficacy of growth factor-mediated bone regeneration is frequently compromised by structural destabilization and loss of bioactivity following adsorption onto biomaterial surfaces. Addressing this challenge requires biomaterials capable of not only delivering osteogenic cues but also preserving protein...
Priyanka Panigrahi, Rituparna Satapathy, D. P. Behera et al.· ACS Applied Bio Materials· 0 citations
Macromolecular crowding significantly influences protein folding, stability, and aggregation within cellular environments. Here, Cellular Retinoic Acid Binding Protein I (CRABP I), a highly stable β-barrel protein with low intrinsic aggregation propensity, was employed to investigate the concentration-dependent effects...
Laxmipriya Prusty, Kalpanarani Dash, Monalisa Mishra et al.· International Journal of Bio...· 0 citations
A magnetically responsive, biocompatible Fe3O4@SiO2 nanoparticle functionalized with a bromocholine-based ionic liquid that combines tunable drug release, biointerfacial compatibility, and rapid healing efficacy, making it a promising candidate for advanced wound therapy.