Intraindividual longitudinal changes of the proteome reveal dynamic markers of biological aging
Proteomic aging clocks have emerged as biomarkers of aging, but most rely on cross-sectional data. Here, we present a proteomic aging clock based on longitudinal measurements of liquid chromatography–mass spectrometry plasma proteomics at up to three time points in the population-based KORA cohort, comprising 9,105 sam...