Importance:
Heart failure with preserved ejection fraction (HFpEF) is common among people with visceral adiposity and type 2 diabetes, yet evidence regarding the benefits of oral formulations of semaglutide in clinical practice and the patients most likely to benefit remains limited.
Objective:
To evaluate the...
N. Krüger, S. Schneeweiss, Yu-Han Kong et al.· Circulation· 0 citations
Patients undergoing percutaneous coronary intervention (PCI) for in-stent restenosis (ISR) lesions have been reported to experience worse outcomes than those treated for de novo lesions. However, no study has yet directly compared these two lesion types when treated in the same patient during the same procedure....
D. Lahu, S. Lahu, F. Simonetti et al.· European Heart Journal· 0 citations
Atherosclerotic cardiovascular diseases (ASCVD), including coronary artery disease (CAD), peripheral artery disease (PAD), and ischemic stroke (IS), account for the majority of global cardiovascular mortality. Although they affect distinct vascular territories, these conditions share overlapping traditional and g...
C. Abrahamian, L. Li, M. Ajayan et al.· European Heart Journal· 0 citations
In patients undergoing PCI for ISR, lesions with 2 or more stent layers were associated with a higher risk of recurrent revascularisation than single-layer lesions, however, patients in the multilayer group did not have a higher risk of cardiac death or myocardial infarction.
D. Lahu, T. Koch, V. Schmidt et al.· European Heart Journal· 0 citations
LLM can be safely and effectively administered in primary care for children with monogenic FH and already low-dose statins resulted in substantial LDL-C reduction, demonstrating real world applicability of guideline recommendations for early start of treatment in FH in a primary care setting.
R. Schmieder, J. Krefting, S. Arens et al.· European Heart Journal· 0 citations
Proteomic aging clocks have emerged as biomarkers of aging, but most rely on cross-sectional data. Here, we present a proteomic aging clock based on longitudinal measurements of liquid chromatography–mass spectrometry plasma proteomics at up to three time points in the population-based KORA cohort, comprising 9,105 sam...
R. Lermer, X. Qian, S. Pusch et al.· bioRxiv· 0 citations
INTRODUCTION AND OBJECTIVES
Percutaneous left atrial appendage occlusion (LAAO) has emerged as an alternative to oral anticoagulants (OACs) in patients with atrial fibrillation (AF). However, up-to-date comparisons are lacking. We performed a systematic review and meta-analysis of randomized clinical trials comparing p...
M. I. Molaro, Cajetan Reichardt, F. Simonetti et al.· Revista Española de Cardiolo...· 0 citations
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