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Open access Sep 2026

Impact of Viral Hepatitis and Thyroid Autoantibodies on Tumor Aggressiveness in Papillary Thyroid Carcinoma

Background and Purpose: To evaluate the impact of chronic viral hepatitis (HBV, HCV) and thyroid autoimmunity on the clinicopathological aggressiveness of papillary thyroid carcinoma (PTC).Methods: This retrospective study included 521 patients with histologically confirmed PTC. Clinicopathological parameters were comp...

Gökçen Güngör Semiz, Sabay Akbaş, Selda Arslan et al. · 0 citations
Open access Sep 2026

Prognostic Value of the Lung Immune Prognostic Index in Metastatic Renal Cell Carcinoma: A Multicentre Cohort Study

Background and Purpose: The Lung Immune Prognostic Index (LIPI), based on derived neutrophil-to-lymphocyte ratio (dNLR) and Lactate Dehydrogenase (LDH), is a recognized biomarker in various malignancies. However, its incremental value over the International Metastatic Renal Cell Carcinoma Database Consortium (IMDC) sco...

Savaş Gökçek, Mehmet Uzun, F. Özalp et al. · 0 citations
Open access Sep 2026

Baseline Inflammatory and Nutritional Indices Show Limited Discrimination for Major Pathological Response and Survival After Neoadjuvant Chemotherapy for Gastric Cancer: A Retrospective Comparison of Eleven Indices

Background/Objectives: While perioperative chemotherapy is standard for locally advanced gastric cancer, no baseline blood marker reliably identifies which patients will respond to treatment. In this retrospective study, we compared eleven inflammatory and nutritional indices against pathological response and survival...

Erkut Demirciler, K. Canaslan, H. I. Ellez et al. · 0 citations
Open access Aug 2026

Preoperative Prediction of Residual Cancer Burden After Neoadjuvant Chemotherapy in Breast Cancer: A Multimodal Machine Learning Approach and Implications for Clinical Decision Support

At equivalent discrimination, the multimodal model was methodologically preferable for preoperative RCB prediction, owing to its stability and interpretability - qualities relevant to trustworthy clinical decision support.

Y. K. Dagdeviren, H. Semiz, E. H. İnan et al. · 0 citations

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