Ethosomal Nanocarriers for Trans-Resveratrol Delivery: Formulation, Physicochemical Characterization, Stability, and In Vitro Release Performance
Background: Trans-resveratrol (3,5,4′-trihydroxystilbene) is a natural polyphenolic antioxidant widely used in anti-aging dermocosmetics for its strong radical-scavenging capacity and its activation of cell-protective pathways such as sirtuin 1 (SIRT1). However, its poor aqueous solubility, photochemical lability, and...