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Open access Sep 2026

307. A new nanoformulation of a brain-penetrating VIPR2 antagonist peptide for the treatment of schizophrenia

Abstract Background Both preclinical and clinical studies have demonstrated a strong link between high expression/overactivation of vasoactive intestinal peptide receptor 2 (VIPR2) and schizophrenia. We recently reported on a brain-penetrant formulation of the VIPR2 antagonist peptide KS-133, which was found to restore...

Y. Ago, Z. Jin, D. Koan et al. · 0 citations

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