Skin wound healing is a complex biological process involving coordinated interactions among fibroblasts, immune cells, keratinocytes, endothelial cells, and extracellular matrix (ECM) components. Chronic and diabetic wounds remain significant clinical challenges due to persistent inflammation, oxidative stress, impaire...
The biological functions, immunoregulatory mechanisms, and therapeutic potential of Tα1 in oncology are summarized to provide an updated perspective on the role of Tα1 as a potential adjunctive immunomodulatory agent in modern cancer immunotherapy.
Sih-Chi Chuang, Pei-Chia Hung, Lekshmi Rethi et al.· European Journal of Pharmaco...· 0 citations
A reproducibly fabricated redox-active nanotherapeutic associated with mitochondrial stress that couples targeted chemotherapy with immune microenvironment remodeling for antitumor efficacy is established.
Andrew E.-Y. Chuang, Szu-Yu Tung, Kai-Yi Tzou et al.· Journal of Nanobiotechnology· 0 citations
The NIR‐activated platform is associated with reduced joint inflammation and edema, attenuated oxidative stress, improved macrophage polarization toward an anti‐inflammatory phenotype, enhanced gait‐related joint function, and preservation of cartilage structure in an OA rat model.
Yu-Wen Tseng, Pei-Wei Weng, Hsien-Tsung Lu et al.· Advanced Healthcare Material...· 0 citations
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