Doxorubicin is an effective anthracycline whose clinical use is limited by organ toxicity, including nephrotoxicity involving oxidative and nitrosative stress, inflammation and tissue remodelling. Coconut water (Cocos nucifera L.) contains antioxidant constituents, but evidence of its effects on doxorubicin-induced ren...
Preye Godgift Egbainmo, H. Ibezim, S. Nwangwu· GSC Advanced Research and Re...· 0 citations
Background: Metabolic syndrome is a major public health concern because the clustering of cardiometabolic risk factors, particularly hypertension and impaired glucose metabolism, substantially increases the risk of cardiovascular disease and type 2 diabetes.
Aim: This study evaluated early clinical and biochemical res...
H. Ibezim, I. O. Eboreime-Oikeh, Chukwudalu Emmanuel Orji et al.· Journal of Advances in Medic...· 0 citations
Background:Chronic inflammation is central to the development of hypertension and its complications, including stroke. The C-reactive protein-to-albumin ratio (CAR), which combines a positive and a negative acute-phase reactant, has emerged as a potential marker of systemic inflammatory burden. However, evidence from s...
C. J. Ofordum, E. Igbokwe, I. K. Ubaoji et al.· Journal of Medicine in Afric...· 0 citations
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