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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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H. Vu

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Open access Oct 2026

Whole-genome 5-hydroxymethylation profiling of human neurons for regulatory and biological insight

While 5-methylcytosine (5mC) DNA methylation is a well-known player in genome stability and transcriptional regulation, the role of 5-hydroxymethylcytosine (5hmC), particularly prevalent in neurons, remains largely unknown. Here, we used long-read Oxford Nanopore Technology (ONT) to profile whole-genome, native 5mC and...

Dennis Klose, Mohammad Hossein Sepehri, Remi-André Olsen et al. · 0 citations

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