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Author

H. Wiendl

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Open access Aug 2026

Heparin-calibrated anti-factor Xa activity as a surrogate marker for direct oral anticoagulant levels in acute stroke care: a large observational single-center study

Direct oral anticoagulants (DOAC) complicate therapeutic decision-making, as rapid assessment of anticoagulant activity is critical in emergency patients, particularly in acute ischemic stroke (AIS). The administration of systemic thrombolysis (IVT) in anti-coagulated patients requires careful risk–benefit evaluation,...

M. Büchsel, Katharina Lisko, H. Gölz et al. · 0 citations
Open access Aug 2026

Distinct Multiomic Signatures of Environmental Exposure Drive Immune Dysregulation and Disease Activity in Early Multiple Sclerosis

While smoking cessation must likely be absolute to reverse pathogenic trafficking signals (such as GPR15 upregulation), the linear effect of BMI suggests that incremental weight loss confers proportional immunologic benefits, which strongly support the integration of lifestyle interventions as a core component of early...

Simon Falk, A. Schulte-Mecklenbeck, P. Ostkamp et al. · 0 citations

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