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Author

H. Wioland

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Open access Sep 2026

Action of cofilin on ADP-Pi-containing actin filaments

In cells, the disassembly of actin filaments is tightly controlled by molecular mechanisms where cofilin plays a central role. Cofilin binds to actin filaments cooperatively, forming clusters that lead to the severing of the filaments. Since cofilin binds preferentially filaments that have hydrolysed ATP and released i...

Inaara T. Kassamaly, Natalia Nojszewska, Thomas Dos Santos et al. · 0 citations
Open access Aug 2026

DAAM1 formin and Ena/VASP proteins assemble functionally distinct actin filaments for focal adhesions

This study investigated how functionally distinct actin nanoscale layers, specified by α-actinin and tropomyosin isoforms, Tpm1.6 and Tpm3.2, are assembled at focal adhesions and found that DAAM1 formin assembles Tpm3.2-actin filaments, whereas Ena/VASP family proteins polymerize α-actinin cross-linked actin filament b...

Le-Chua Xiang, Parijat Biswas, H. Wioland et al. · 1 citation

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