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Author

H. Yamazaki

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2 papers indexed here

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Review Open access Sep 2026

[Metabolic Activations and Pharmacokinetics of Drugs Using Data-driven Modeling].

Pharmacological and toxicological assessments of a wide array of chemicals typically involve estimating human clearance through allometric extrapolation of in vivo animal data, using empirical compartmental and physiologically based pharmacokinetic (PBPK) models. Parameters for pharmacokinetic absorption, distribution,...

H. Yamazaki · 1 citation
Review Open access Oct 2026

[Pharmacokinetics and Metabolic Activations of Drugs in Pharmacology and Toxicology].

The parameters for the absorption, distribution, and metabolic clearance of a wide array of chemicals can be calculated and integrated into a physiologically based pharmacokinetic (PBPK) model that simulates plasma drug concentration over time. Typically, pharmacological and toxicological assessments of chemicals invol...

H. Yamazaki · 0 citations

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