Open access
Oct 2026
A nuclear ERK-ATF5 axis coordinates mitochondrial metabolism and thermogenic gene expression in brown adipocytes.
Obesity and diabetes arise from disrupted energy homeostasis, underscoring the need to identify mechanisms that enhance energy expenditure. Brown adipose tissue dissipates energy through mitochondria-dependent non-shivering thermogenesis; however, the transcriptional regulators coordinating this process remain incomple...
Hyo Ju Jang, Yeongjun Suh, Jing-Wen Tian et al.
· Journal of Endocrinology · 0 citations