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Hadi Nazem-Bokaee

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Open access Aug 2026

VariantFlux: A genotype-first modelling workflow for predicting the impact of genetic variations on human metabolism

VariantFlux, a workflow that integrates ancestry-aware variant interpretation into genome-scale metabolic modelling to generate personalised, variant-constrained kidney reconstructions, is presented, allowing exploratory, mechanistic prediction of how naturally occurring genetic variation reshapes human metabolism.

Hadi Nazem-Bokaee · 0 citations

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