Hai-Feng Xu

A candidate CD4⁺ T-cell gene expression panel for multiple sclerosis highlights MgADP-associated genes.

Multiple sclerosis (MS) is an autoimmune disease characterized by immune cell dysregulation. HLA class II alleles drive the disease risk, thereby highlighting CD4+ T cells as central contributors to MS initiation. While genome-wide association studies have identified additional non-HLA genetic risk loci, the mechanisms...