Author

Hai Jin

3 papers indexed here

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Review Open access Sep 2026

Exosome-mediated metabolic-immune regulatory axis: mechanisms of gastric cancer progression and resistance and targeting strategies

Gastric cancer (GC) is characterized by marked heterogeneity and frequent resistance to chemotherapy and immunotherapy. Exosomes mediate intercellular communication between tumor, stromal, and immune cells and may couple metabolic adaptation to immune suppression. This review synthesizes evidence for a bidirectional ex...

Shun Yao, Hong-Yu Chai, Lu-Lu Tang et al. · Frontiers in Immunology · 0 citations

Open access Sep 2026

Integrated murine and human transcriptomics prioritizes a multicellular mitochondrial signature associated with immune and parenchymal features in NAFLD/MASLD

Metabolic dysfunction-associated steatotic liver disease (MASLD), historically termed nonalcoholic fatty liver disease (NAFLD), involves metabolic dysregulation, mitochondrial stress, and immune remodeling. However, disease-associated multicellular transcriptional programs and their spatial context remain incompletel...

Lu-Lu Tang, Guang-Yan Luo, Li Zhang et al. · Clinical and Experimental Me... · 0 citations

Review Open access Sep 2026

The Role of Mitochondrial Dysfunction in Hepatocellular Carcinoma: From Pathogenesis and Drug Resistance to Targeted Therapeutic Strategies

Abstract Hepatocellular carcinoma (HCC) is characterized by high malignancy and widespread drug resistance at advanced stages, posing formidable challenges in clinical diagnosis and treatment. Mitochondrial dysfunction is a core driver of HCC initiation and drug resistance. However, how its plasticity dynamically regul...

Si-Yu Zhao, Qian Liu, Jing Li et al. · Journal of Hepatocellular Ca... · 0 citations