Sep 2026
A novel cold-adapted esterase FE2495 from Antarctic Flavobacterium ardleyense A2-1: Biochemical characterization and structural basis for cold-adaptation.
Comparative structural analysis with a thermophilic homolog Est5250 revealed that FE2495 possessed a large catalytic pocket, fewer hydrogen bonds and salt bridges, and a distinct amino acid composition depleted in arginine, providing a possible explanation for its broad temperature tolerance.
Yuan-Fang He, Zeyuan Sun, Sheng-Cai Gao et al.
· International Journal of Bio... · 0 citations