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Hai-Ning Fan

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Open access Sep 2026

PD-L1+ neutrophils at the invasive margin drive contact-dependent CD8+ T cell exhaustion in hepatic alveolar echinococcosis

Introduction Hepatic alveolar echinococcosis (HAE), a lethal chronic helminth infection caused by Echinococcus multilocularis, is characterized by pronounced local immune evasion and progressive CD8+ T cell exhaustion at the parasite?host invasive margin. However, the spatial cellular network and core regulatory subset...

Da-Lin Shi, Chengwei Tie, Ming-Quan Pang et al. · 0 citations

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