Hai-Qin Chen

Reprogramming energy system for growth and bioproduction from CO₂ and methanol in Escherichia coli

Microbial CO₂ assimilation provides a strategy for sustainable biomanufacturing. However, CO₂ reduction requires substantial energy input, while native energy systems are tightly regulated and extensively consumed by endogenous metabolism, limiting assimilation efficiency. Here, we design and construct an orthogonal en...