Hai-Rong Cheng

Systematic metabolic engineering of Yarrowia lipolytica for highly efficient biosynthesis of mannitol from glucose.

Mannitol is widely utilised in the food and pharmaceutical industries. Current commercial production primarily depends on chemical synthesis, a process that is expensive, environmentally detrimental, and requires high-temperature/pressure as well as complex purification steps. While microbial production of mannitol has...