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Hai-Yan Wu

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Review Open access Sep 2026

Spatial immune biomarkers in triple-negative breast cancer: emerging evidence, technology trade-offs, and barriers to clinical translation

Triple-negative breast cancer (TNBC) is an immunogenic but clinically heterogeneous breast cancer subtype. Stromal tumor-infiltrating lymphocytes (TILs), PD-L1 expression, and tumor mutational burden provide useful but incomplete summaries of the tumor immune microenvironment. Spatial immune biomarkers retain tissue ar...

Liu-Hai Zeng, Wei Lin, Shi-Hang Xue et al. · 0 citations

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