Oct 2026
Histone lactylation-upregulated CEBPB transcriptionally activates CXCL12 and p21 to modulate vascular smooth muscle cell senescence and macrophage polarization.
BACKGROUND Abdominal aortic aneurysm (AAA) represents a widespread vascular disorder associated with high significant mortality rates, and the phenotypic transformation of vascular smooth muscle cells (VSMCs) acts as a crucial pathological characteristic during the advancement of this condition. Recent studies suggest...
Yong-Xin Han, Jia-Cheng Wang, Ru-Chen Li et al.
· Cellular Signalling · 0 citations