Haimen Yezihalem

Resolvin E1 promotes the resolution of inflammation and enhances myogenic responses during aged skeletal muscle regeneration.

Efficient muscle regeneration relies on the coordinated crosstalk between muscle stem cells (MuSCs) and their surrounding niche. Specialized pro-resolving mediators (SPMs), like resolvins, serve as critical autocrine and paracrine signals within this microenvironment, with macrophages acting as one of the primary sourc...