Open access
Sep 2026
A computational framework for proteome-wide target profiling of natural products: mechanistic and therapeutic insights into ginsenosides
Abstract Natural products (NPs) serve as valuable sources of pharmacologically active compounds, yet their therapeutic potential remains constrained by incomplete knowledge of their molecular targets. To address this, a computational framework based on evolutionary chemical binding similarity (ECBS) is developed to gen...
Dohyeon Kim, Charuvaka Muvva, Jung-Seok Yang et al.
· Briefings in Bioinformatics · 0 citations