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Author

H. Berman

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Open access Aug 2026

Immune profiling by bulk RNA-seq and multiplex immunofluorescence imaging across multiple cancer types

Background Immune cell populations within the tumor microenvironment (TME) critically determine cancer prognosis and therapeutic response. Although multiplexed immunohistochemistry (mIHC) provides spatial immune profiling and bulk RNA sequencing methods offer comprehensive cellular characterization, comparative studies...

C. Gaspar, Benson Z. Wu, Simone C. Stone et al. · 0 citations
Aug 2026

Germline BRCA1 Mutation Deregulates Irradiation–Induced Cell Cycle Checkpoints in Human Mammary Luminal Progenitors

A lineage-resolved monolayer culture system is established that enables propagation of primary human mammary epithelial populations while preserving lineage identity across passages and provides a functional framework for determining critical events in the expansion of genomically altered mammary epithelial cells in th...

Abhijith Kuttanamkuzhi, Bowen Zhang, Kelvin Yeung et al. · 0 citations

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