Open access
Sep 2026
Network-guided identification and multi-targeting of cell cycle regulatory hubs in obesity-linked colorectal cancer
Purpose: Obesity-associated colorectal cancer (CRC) involves complex molecular networks that limit the effectiveness of single-target therapies. This study aimed to develop an integrative computational pipeline for identifying key regulatory hubs and designing a multi-target-directed ligand (MTDL) capable of simultaneo...
Merve Uça Apaydın, Huseyin Guner, Resat Unal et al.
· Cukurova Medical Journal · 0 citations