Open access
Sep 2026
Homeobox a4 is proapoptotic in the AC16 human cardiomyocyte cell line and a key effector of the MIAT/miR-150 axis in murine myocardial infarction
MicroRNA-150-5p (miR-150) was correlated with heart failure (HF) severity in humans. Left ventricular homeobox a4 (HOXA4) was upregulated in patients with HF. Gain-of-function mutants in myocardial infarction-associated transcript (MIAT) were associated with increased risk of myocardial infarction (MI) in humans. O...
S. Kawaguchi, Marisa N. Sepúlveda, Taiki Hayasaka et al.
· Cell Death & Disease · 0 citations