Adipose tissue plays a central role in energy homeostasis, influencing metabolism, thermoregulation, and overall health. White adipose tissue (WAT) primarily stores energy, while brown adipose tissue (BAT) dissipates energy through heat production. This thermogenic capacity of BAT is mediated by uncoupling protein 1 (U...
Hamid Khan, Adeel Ahmad, M. Kiyani et al.· Current molecular medicine· 0 citations
Sleep loss is a major risk factor for neurodegenerative diseases like Alzheimer's disease (AD) and Parkinson's disease (PD), accelerating cognitive impairment with neuropathology. Cumulative sleep loss impairs the glymphatic system, reduces amyloid-β clearance, and enhances the neuroinflammatory response, all of which...
Adeel Ahmed, Xiao-Qin Fu, Hamid Khan et al.· Current Neuropharmacology· 0 citations
ASD has been associated with alterations of the microbiota-gut-brain axis, a bidirectional system that links gut microbiota to neural, endocrine, and immune pathways. Multi-omics studies indicate that most of the ASD affected individuals have lower levels of beneficial taxa, including Bifidobacterium, Lactobacillus gem...
Hamid Khan, Yumei Wang, Iqra Iftikhar et al.· Current Neuropharmacology· 0 citations
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