Author

Han-Bin Lee

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Open access Oct 2026

Linkage disequilibrium moderates how evolving genetic background shapes variant-level architecture

This work develops a model of linkage LD evolution accounting for stabilizing selection, recombination, and genetic drift that deduces the genetic architecture of individual variants subject to the co-evolving genetic background.

Han-Bin Lee, Jonathan Terhorst · bioRxiv · 0 citations