Author

Han Chen

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Review Open access Aug 2026

Avoidance of cardiac toxicity during the application of immune checkpoint inhibitors: a safety systematic review combining network meta-analysis and pharmacovigilance study

Background Although immune checkpoint inhibitor (ICI) therapy has revolutionized cancer treatment, the incidence of cardiac toxicity associated with ICIs remains unclear. This study aimed to evaluate the cardiac toxicity risks associated with ICI and identify the most common types of cardiac toxicity caused by ICI. A f...

Han Chen, Yongqi Shan, Han-Fang Xu et al. · Frontiers in Immunology · 0 citations

Open access Aug 2026

Single vs. dual antiplatelet therapy before DOAC initiation in acute ischemic stroke with atrial fibrillation: a retrospective cohort study

DAPT prior to DOAC initiation was associated with higher 90-day favorable functional outcome without excess bleeding risk, but this association was not independent of baseline stroke severity after multivariable adjustment, suggesting that the crude benefit was largely attributable to selection bias rather than a true...

Guanxin Hou, Adili Tuersun, Zuo-jun Wang et al. · Frontiers in Neurology · 0 citations