Engineered microbial therapies provide a promising strategy for in situ production of therapeutic molecules at disease sites; however, their clinical translation remains limited by insufficient retention at target tissues and the lack of external control after administration. Here, we develop a wearable bioelectronic-a...
Hong-Xiang Li, Chao Zhang, Hai-Han Yao et al.· Journal of Colloid and Inter...· 0 citations
Outer membrane vesicles (OMVs), as promising delivery vectors, have been extensively explored for the delivery of nucleic acid-based drugs, particularly the RNA therapy. However, RNA-loaded OMVs delivery systems derived from in vivo engineered bacteria lack the controllable way for regulating target RNA synthesis. Co...
Data-driven protein engineering has enabled biosensors that directly couple molecular recognition with measurable signal outputs, providing a powerful strategy for rapid protein analysis. However, their integration into automated and portable analytical systems remains limited. Here, we developed an integrated photoele...
