A wspA mutation in a clinical isolate of Pseudomonas aeruginosa results in rugose small colonies and enhances biofilm formation
ABSTRACT Pseudomonas aeruginosa is a major multidrug-resistant pathogen whose biofilm formation complicates treatment. Rugose small colony variants (RSCVs) exhibit enhanced biofilm production and resistance, posing significant clinical challenges; however, their formation mechanisms in clinical strains remain incomplet...