Restricted mean survival time ratio in oncology cost-effectiveness analysis: stability and data-driven support for treatment-effect waning modeling and survival extrapolation
Abstract Objectives We examined long-term treatment-effect patterns relevant to treatment effect waning (TEW) modeling in oncology health technology assessment (HTA), compared the dispersion and update stability of hazard ratios (HRs) and restricted mean survival time ratios (RMSTRs), and developed prediction models to...