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Author

Han-Qiao Shao

2 papers indexed here

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Open access Oct 2026

Restricted mean survival time ratio in oncology cost-effectiveness analysis: stability and data-driven support for treatment-effect waning modeling and survival extrapolation

Abstract Objectives We examined long-term treatment-effect patterns relevant to treatment effect waning (TEW) modeling in oncology health technology assessment (HTA), compared the dispersion and update stability of hazard ratios (HRs) and restricted mean survival time ratios (RMSTRs), and developed prediction models to...

Ming-Ye Zhao, Han-Qiao Shao, T. Shao et al. · 0 citations
Open access Sep 2026

Limited Assessment of Proportional Hazards Despite More Frequent Violations Identified in Updated Oncology Trial Analyses: Frequency, Patterns, and Statistical Implications.

Prior studies suggest that proportional-hazards violations (PHVs) occur in oncology randomized controlled trials (RCTs) and may affect conclusions, but evidence has largely focused on initial reports rather than updated analyses. We examined PH testing practices, frequency, patterns, and statistical implications of PHV...

Ming-Ye Zhao, Yun-Lin Jiang, T. Shao et al. · 0 citations

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