Endothelial cells regulate hemodynamics, inflammation, and vascular barrier integrity, thereby playing a central role in vascular homeostasis. Pathological conditions, including hypertension, hyperglycemia, and hyperlipidemia, induce metabolic reprogramming in these cells, altering the balance among glycolysis, fatty a...
Hong-Yu Chen, Ying-Liang Zhao, Cheng-Xin Ge et al.· Reviews in cardiovascular me...· 0 citations
Atherosclerosis (AS) is a chronic vascular pathology and a leading cause of global cardiovascular morbidity and mortality, with dysregulated lipid metabolism acting as a primary driver of its progression. 5-Methoxyflavone (5-MF), a natural flavonoid, exhibits known lipid-modulating and antioxidant properties; however,...
Hao-Yang Zheng, Yi-Qing Zhao, Yu-Fei Huo et al.· Biochemical and Biophysical...· 0 citations
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