Skip to content
Log in
Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Hanzhi Wang

View on Semantic Scholar

3 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Open access Oct 2026

The recoverable resolution of cellular perturbation-response prediction

Virtual cell models aim to predict how cells respond to perturbations, yet accurate prediction of post-perturbation gene expression can conceal failures to recover context-specific responses. Here we identify context geometry compression (CGC), in which models preserve cellular identity and shared perturbation effects...

Yong-Qi Huang, Han-Zhi Wang, Chen-Yu Li et al. · 0 citations
Open access Aug 2026

Virtual-cell models compress unseen intervention geometry through a target-specific generalization bottleneck

Predictive models of cellular perturbation are often judged by how closely they reconstruct molecular states after unseen interventions. We show that high state-level similarity can coexist with loss of the relationships that distinguish perturbations, a failure we term Intervention Geometry Compression (IGC). Across e...

Yong-Qi Huang, Hanzhi Wang, Parker C. Wilson · 0 citations
Open access Aug 2026

High-Specificity Detection of Chromosomal Mosaicism Reveals Cell-Type-Specific Genomic Alteration Patterns in Aging Tissues

Mosaic chromosomal alterations (mCAs) increase with age and are associated with multiple diseases, yet the cell types and states that harbor these alterations remain largely unknown. Because mCAs arise in individual cells prior to clonal expansion, they are typically rare and obscured in bulk data. We develop CHASM, a...

Xinyi E. Chen, Hanzhi Wang, Yilin Yang et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.